Curcumin may help lower inflammation

A study published in Clinical Nutrition shows that curcumin may lower inflammation, which contributes to a wide range of illnesses such as heart disease and joint pain.


The researchers recruited 117 participants who had been diagnosed withmetabolic syndrome. Half of the participants were given pills containing one gram of curcumin powder, and the other half were given a placebo pill. All the participants took the supplements every day for eight weeks. At the beginning of the study and again at the end, the researchers measured levels of three blood markers of inflammation-C-reactive protein (CRP), superoxide dismutase (SOD), and malondialdehyde (MDA).

The researchers found that the participants who took curcumin had improved blood levels of all three biomarkers as well as reduced fasting blood sugar and hemoglobin A1c, a measure of long-term blood sugar levels. The placebo group had higher glucose and levels of one of the inflammation markers, and no changes in the other markers.

In addition, due to CRP’s importance as a risk marker and risk factor of cardiovascular disease, a random-effects meta-analysis of clinical trials was performed to estimate the overall impact of curcuminoid therapy on circulating concentrations of CRP. The results from eight previous studies confirmed that curcumin had shown a significant reduction of CRP
concentrations in a total of 281 patients.

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